Mediken Inc. was established by Yuichi Hyakusoku in October 1991.The name Mediken is short for " Media Kenkyujo ", which in Japanese translates to "Media Laboratories".

In 1992, Ebara Corporation, one of the leading global companies in Japan, invested in Mediken to handle the service of Intervac Vacuum Systems in cooperation with Ebara's subsidiary, Matsuzaka Co. Ltd. (currently called Matsubo). Mediken opened its first office at the Fujisawa Plant of Ebara in Kanagawa Prefecture.

On May 1st 1994, President Hyakusoku bought all the stock and became the sole owner of Mediken. Then moved the offices to Shinbashi in Tokyo. After the relocation, Mediken has started importing instruments and production equipment for the Magnetic and optical recording industries.

In 2000, a new subsidiary company called Medic was established to handle general installation services, vacuum system transfers, and used equipment sales. A large warehouse that stocks used equipment is located at Medic.

In 2001, Mediken invested to build a R&D facility in the affiliated company, Mekong in Yamagata for the manufacturing of custom build equipment, mainly the wet process for Semicon and FPD, which equips with clean room, DI water and various instrument.

In 2008, became the distributor for Flexstar Technology Inc, which is well established HDD tester manufacturer in Silicon Valley.

In 2009, the sales reached 5 billion yen at the end of 18th fiscal term and received the capital investment from Bank of Tokyo Lease to strengthen the financial capability.
On July 1st, became the distributor for Dr.Schenk GmbH, German Instru-ment manufacture which is well known in Optical disk and Solar Panel indus-try.

In 2010, Yamanashi technical center was opened.
On April 30th 2010, moved the offices to Uchisaiwaicho, Chiyoda-ku.On December 20th 2010, using Dr. Schenk's technology, our own handling & inspection system was developed and delivered for multi-layers sheet applica-tion.

On December 2013, received the large order from chinese leading glass coating
company for the coating, polishing and inspection system.

In 2014, delivered the Inspection System for Li Ion Battery Separator Films.

On March 2015, moved the office to Kyobashi, Chuo-ku, Tokyo
On December 2015, delivered the Sputtering system for the Triple-layer BD.

On January 2016, delivered the Inspection system for the Barrier film.
On March 2016, opened the Demonstration room in Tokyo.

On April 2016, delivered the Inspection system for the Substrate.
On February 2017, delivered the Inspection system for the Fine Mesh.

On February 2018, moved the office and demonstration room To Fujisawa, Kanagawa.

On March 2019, delivered the Inspection system for the PET Film Line.